HEDS is part of the School of Health and Related Research (ScHARR) at the University of Sheffield. We undertake research, teaching, training and consultancy on all aspects of health related decision science, with a particular emphasis on health economics, HTA and evidence synthesis.

Thursday, 10 January 2019

NICE say “yes” to regorafenib for previously treated advanced hepatocellular carcinoma

This was a rapid review of TA514, which gave a resounding “no”.  Bayer came back with a more generous PAS and a submission that used the Committee’s preferred assumption.  The ERG undertook some further analyses which allowed the Committee to conclude, rightly or wrongly, that the most plausible ICER is below £50,000 per QALY gained.

ScHARR-TAG were the ERG and the additional analyses were undertaken by Matt Stevenson, Paul Tappenden and Andrew Rawdin.  Further details are available here.