HEDS is part of the School of Health and Related Research (ScHARR) at the University of Sheffield. We undertake research, teaching, training and consultancy on all aspects of health related decision science, with a particular emphasis on health economics, HTA and evidence synthesis.

Friday, 20 July 2018

The University of Sheffield ranked one of the best universities for teaching in Europe

The University of Sheffield was named 11th out of 250 institutions across eight European countries in the new rankings, underlying the university's reputation for outstanding teaching.
The new rankings from The Times Higher Education are the first international ranking to measure the quality of teaching across the world. The rankings, which places the University of Sheffield joint ninth in the UK, draw on data from the European Student Survey. The survey examines a range of key issues including students’ engagement with their studies, their interaction with teachers, the quality of services at the institution and their opportunities to develop skills which help prepare them for a career after university.
The results were warmly welcomed by Vice-President for Education, Professor Wyn Morgan and President and Vice-Chancellor, Professor Sir Keith Burnett, who said:
"I am genuinely delighted to see the commitment of extraordinary teachers and colleagues at Sheffield acknowledged in this significant international review of teaching quality in universities. This wonderful result reflects not only dedicated teaching but the way staff work with students to challenge and inspire, listening to their concerns and seeking new ways to connect what they are learning to the challenges they will face after graduation.
Image of Students at Sheffield
Students at Sheffield
"Good teaching is not a product. It takes great effort on the part of teacher and student, the latest learning resources, technologies, facilities and sometimes intensive support. The results though are felt throughout the lives of our students and I am never more proud than when graduates around the world speak with pride and affection about those who taught them, challenged them and gave them the tools they took into their careers."
According to The Times Higher Education, the new Teaching Ranking assesses the student teaching and learning environment and student outcomes, and was designed to answer the questions that matter most to students and their families when making one of the most important decisions of their lives – who to trust with their education.
Phil Baty, Editorial Director of global rankings at Times Higher Education, added: “While teaching is perhaps the single most important mission of any university, no other international ranking focuses entirely on teaching and learning, placing student needs at its very heart. This initiative is an important world first, offering a much-needed fresh perspective on excellence in higher education. The University of Sheffield does particularly well in our ‘outcomes’ score, for successful student progress - but it also does very well in our student engagement survey, demonstrating that its students feel stretched, challenged and stimulated by their courses.”
The ranking includes universities in countries that are a full member of both the European Higher Education Area and the Organisation for Economic Cooperation and Development, and are classified as a “developed economy” by the United Nations. Building on the success of the THE US Student Survey, which has been running for three years, the inaugural European Student survey captured detailed responses from 30,000 students in more than 10 European countries. The survey also covers a wide range of core questions, focused not on student satisfaction, but on their engagement with learning, and how much they are stretched and challenged in the classroom.
The full results were announced at the Times Higher Education Teaching Excellence Summit.
In June, The University of Sheffield was ranked as one of the best universities in the world in the QS World University Rankings 2019, strengthening its position as a leading global university for teaching and research. The results placed the University as the 13th best institution in the UK and 75th in the world, a rise from last year’s placing of 82nd. These results position it as the number one University in Yorkshire and Humber and among the top 7.5 per cent of all the universities in the QS World University Rankings.
The University of Sheffield also recently celebrated success in The Guardian University Guide 2019 after subjects from across the institution were ranked among the UK’s best for courses. Earlier in the year, the University of Sheffield Students' Union was voted top nationally for the tenth consecutive year by the Times Higher Education Student Experience Survey 2018.

Thursday, 19 July 2018

June’s CEAs.....

Our quick search for CEA’s published in June uncovered 52 articles.   In the right-hand column of this blog is a CEA Archive, which includes our CEA search results by month.  Below are those in our areas of interest.
  • De Mil R, Guillaume E, Guittet L, Dejardin O, Bouvier V, Pornet C, et al. Cost-Effectiveness Analysis of a Navigation Program for Colorectal Cancer Screening to Reduce Social Health Inequalities: A French Cluster Randomized Controlled Trial. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2018;21(6):685-91.
  • Leurent B, Gomes M, Carpenter JR. Missing data in trial-based cost-effectiveness analysis: An incomplete journey. Health economics. 2018;27(6):1024-40.
  • McKay AJ, Hogan H, Humphries SE, Marks D, Ray KK, Miners A. Universal screening at age 1-2 years as an adjunct to cascade testing for familial hypercholesterolaemia in the UK: A cost-utility analysis. Atherosclerosis. 2018.

Tuesday, 17 July 2018

#Supervisionaires at HEDS

HEDS Colleagues Dr Suzy Paisley (top left), Dr Katy Cooper (bottom right) and Professor Aki Tsuchiya (top right) are among ScHARR supervisors and professional services staff have been recognised by their doctoral students in a new initiative led by the Think Ahead team at the University of Sheffield. They led a project called #SuperVisionaries to find out about and share examples of good supervision and its impact on doctoral researchers. The Think Ahead team asked all the doctoral students at the University of Sheffield to tell them who was doing a great job and making a difference, and received over 200 responses!
Dr Guccione who was involved in the project commented, “It’s important to recognise that there are reasons a great supervisor may not have been recognised, and that there are excellent supervisors in ScHARR who are not featured here. Awareness of the project might not be uniform across all PGRs, or perhaps student-supervisor teams are in the regular habit of saying thanks to each other personally, rather than anonymously.”
So whilst there will be other examples of excellence in supervision that were not put forward for this project, it is great to see so many supervisors and professional services staff recognised for their hard work in supporting students.

Monday, 16 July 2018

Research to Support Policy - Funding Success for HEDS

Image of NIHR Logo and 70 years of the NHS

HEDS have renewed their collaboration with The Centre for Health Economics (CHE) as part of The National Institute for Health Research new set of 13 NIHR Policy Research Units to undertake research to inform decision-making by government and arms-length bodies.
The £65 million investment over five years will ensure that the government and arms-length bodies have the best possible information and evidence available when making policy decisions about health and social care.

The 13 new NIHR units will provide both a long-term resource for policy research and a rapid-response service to provide evidence for emerging policy needs. The units, which are considered to be an exemplar of good practice in government, will also offer advice to policy makers and analysts on the evidence base and options for policy development.

The units will cover a range of specialisms and conditions, such as behavioural science, adult social care, older people and frailty, and cancer awareness, screening and early diagnosis.
Each university-based NIHR Policy Research Unit will host a multidisciplinary team of researchers from collaborating institutions, to create a critical mass of experts for research in priority areas for health and social care policy.

The units will work closely with the Department of Health and Social Care to determine priorities and provide evidence directly to the Secretary of State for Health, government departments and arms-length bodies, such as NHS England and Public Health England.

Examples of the types of research topics the units may undertake include how behavioural science can help maximise the impact of clinical consultations; how outcomes of social care services vary for different groups of people; and how social inequalities affect the uptake of cancer screening.
Professor Chris Whitty, Chief Scientific Adviser for the Department of Health and Social Care, said:
Patients and the public deserve a healthcare system that is informed by the latest research and evidence. The NIHR Policy Research Units will make sure that Government decisions affecting our health and care are robust and evidence based.”

These new units, which will begin work in January 2019, join two existing units in mental health and obesity.

Thursday, 12 July 2018

Latest publications from HEDS for June

Image of the front cover of BMC Public Health Journal
© Springer Nature                      
Bates, S., Holmes, J., Gavens, L., De Matos, E. G., Li, J., Ward, B., Hooper, L., Dixon, S. & Buykx, P. (2018) Awareness of alcohol as a risk factor for cancer is associated with public support for alcohol policies. BMC Public Health. [Online] 18 (1),

Bermejo, I., Ren, S., Simpson, E., Clowes, M., Scott, D. L., Young, A. & Stevenson, M. (2018) Sarilumab for Previously-Treated Moderate or Severe Rheumatoid Arthritis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. Pharmacoeconomics. [Online]  Available from: https://www.ncbi.nlm.nih.gov/pubmed/29882210.

Devlin, N., Brazier, J., Pickard, A. S. & Stolk, E. (2018) 3L, 5L, What the L? A NICE Conundrum. PharmacoEconomics. [Online] 36637–640.

Fuller, G. W., Goodacre, S., Keating, S., Perkins, G., Ward, M., Rosser, A., Gunson, I., Miller, J., Bradburn, M., Thokala, P., Harris, T., Carson, A., Marsh, M. & Cooper, C. (2018) The ACUTE (Ambulance CPAP: Use, Treatment effect and economics) feasibility study: a pilot randomised controlled trial of prehospital CPAP for acute respiratory failure. Pilot and Feasibility Studies. [Online] 4 (1), . 
Image of Value in Health Journal

Gray, L. A., Wailoo, A. & Hernandez, M. (n.d.) Mapping the FACT-B instrument to EQ-5D-3L in Patients with Breast Cancer using Adjusted Limited Dependent Variable Mixture Models vs Response Mapping. Value in Health. http://eprints.whiterose.ac.uk/131975/

Hernandez-Villafuerte, K., Fischer, A. & Latimer, N. R. (n.d.) Challenges and Methodologies Using Progression Free Survival As A Surrogate For Overall Survival In Oncology. International Journal of Technology Assessment in Health Care. http://eprints.whiterose.ac.uk/130810/

Keetharuth, D., Taylor Buck, E., Acquadro, C., Conway, K., Connell, J., Barkham, M., Carlton, J., Ricketts, T. N., Barber, R. & Brazier, J. E. (n.d.) Integrating qualitative and quantitative data in the development of outcome measures: the case of the Recovering Quality of Life (ReQoL) measures in mental health populations. International Journal of Environmental Research and Public Health. (Special Issue ‘Mental Health and Social Care and Social Interventions’), . https://www.ncbi.nlm.nih.gov/pubmed/29949892

Image of The European Journal of Health Economics journal
© Springer
Kharroubi, S. & Rowen, D. L. (n.d.) Valuation of preference-based measures: Can existing preference data be used to select a smaller sample of health states? The European Journal of Health Economics. https://www.ncbi.nlm.nih.gov/pubmed/29980950

Lawton, K., Royals, K., Carson-Chahhoud, K. V, Campbell, F. & Smith, B. J. (2018) Nurse-led versus doctor-led care for bronchiectasis. Cochrane Database of Systematic Reviews. [Online] 2018 (6), . https://www.ncbi.nlm.nih.gov/pubmed/29926473

Pennington, R. M., Collins, B., Leigh, S., Martin, A. P., Owen, L., Fischer, A., Sumnall, H. & Bates, G. (2018) The cost-effectiveness of seven behavioural interventions to prevent drug misuse in vulnerable populations. International Journal of Drug Policy. [Online] 5742–50.  Available from: https://www.sciencedirect.com/science/article/pii/S0955395918300987

Rowen, D. L., Labeit, A., Stevens, K., Elliot, J., Mulhern, B., Carlton, J., Basarir, H. & Brazier, J. (n.d.) Estimating a preference-based single index measuring the quality of life impact of self-management for diabetes. Medical Decision Making. https://www.ncbi.nlm.nih.gov/pubmed/29957107

Image of front cover of PharmacoEconomics
© Adis
Stevens, J. W. (n.d.) Using evidence from randomised controlled trials in economic models: What information is relevant and is there a minimum amount of sample data required to make decisions? PharmacoEconomics. https://www.ncbi.nlm.nih.gov/pubmed/29926358

Tappenden, P., Carroll, C., Stevens, J., Simpson, E., Thokala, P., Wong, R., Wright, J. & Auer, R. (2018) Ibrutinib for Treating Waldenstr├Âm’s Macroglobulinaemia: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics. [Online] 1–12. https://www.ncbi.nlm.nih.gov/pubmed/29951793

Tes, D., Kratkiewicz, K., Aber, A., Horton, L., Zafar, M., Arafat, N., Fatima, A. & Avanaki, M. R. N. (2018) Development and Optimization of a Fluorescent Imaging System to Detect Amyloid-╬▓ Proteins: Phantom Study. Biomedical Engineering and Computational Biology. [Online] 9117959721878108–117959721878108. https://www.ncbi.nlm.nih.gov/pubmed/29977121

Tuesday, 10 July 2018

Dr Chris Carroll announced as HEDS new Deputy Director

Image of Dr Chris Carroll
Dr Chris Carroll
Dr Chris Carroll has taken over from Professor Eva Kaltenthaler as HEDS Deputy Director. Professor Kaltenthaler retired at the end of June after working for ScHARR for over two decades. Dr Carroll will support HEDS Director Dr Phil Shackley and act as Director in Dr Shackley's absence. 

Dr Carroll said: "I look forward to working with Phil and the rest of the section's management team".

Dr Carroll joined ScHARR in 2004 and was appointed as a Research Fellow in 2007. In early 2011 he was appointed Senior Lecturer in Health Technology Assessment (HTA) and Course Director of the MSc in International Health Technology Assessment, Pricing and Reimbursement (iHTA). In 2014 Dr Carroll was promoted to Reader and made a University Senate Fellow for Excellence in Learning and Teaching

Dr Carroll stepped down as Course Director of the iHTA programme in mid-2015 and returned to working for the ScHARR Technology Assessment Group (TAG) conducting appraisals for NICE. Since 2017 he has also been the Lead for the systematic reviewers in HEDS.

Friday, 6 July 2018

Economic evaluation in health care - A series of short animations on the topic

Our own Dr Nick Latimer created a series of animations on the topic of Economic evaluation in health care. The series of five videos have been very popular on his Youtube Channel can be viewed below and on our ScHARR Library YouTube Channel.

Wednesday, 4 July 2018

Dr Matt Franklin announced as our new Director of our Masters in Health Economics and Decision Modelling (HEDM)

Image of Dr Matt Franklin
Dr Matt Franklin
Dr Matt Franklin has taken over as Director of our Masters in Health Economics and Decision Modelling (HEDM).

The MSc in Health Economics and Decision Modelling (HEDM) is one of a suite of 3 MSc's that the University of Sheffield offer in the field of health economics, decision modelling and health technology assessment (HTA), the others being the on-line MSc in International Health Technology Assessment, Pricing and Reimbursement and the more econometrics-focused MSc in Economics and Health Economics. 

Dr Franklin said: "I am delighted to take over from Dr John Stevens as Director of the HEDM Masters course from the 1st July 2018. John has done an excellent job in the role over the last 3 years and I hope to maintain his high and impressive standards as I take over the role. As an alumni of the Economic and Health Economics (E&HE) Masters course (Director then and now being Prof Aki Tsuchiya - someone who has influenced my career as a health economist more than I think she knows), which I completed almost 10 years ago."

"I remember my time as a Masters student at the University of Sheffield and I hope to use this experience to my advantage. I will be looking to apply my 10 years of health economic experience in an alumni, research, and teaching capacity to the Director of HEDM role. If I can serve the staff and students associated with the HEDM course as well as those associated with the E&HE course served me as a student 10 years ago, this is the best for which I could hope."

Tuesday, 3 July 2018

Cochrane Collaboration Issue 6, 2018…

….is complete.  The website lists reviews and protocols.  Of note are……
  • Botulinum toxins for the prevention of migraine in adults
  • Workplace interventions for reducing sitting at work
  • Parenteral opioids for maternal pain management in labour
  • Interleukin inhibitors for psoriatic arthritis
  • Stem cell therapy for multiple sclerosis
  • Paracetamol, NSAIDS and opioid analgesics for chronic low back pain: a network meta‐analysis

Monday, 2 July 2018

New Project - Colorectal Cancer risk scores to improve efficiency of screening programme

CRC risk scores to improve efficiency of screening programme  
Sponsor: Bowel Cancer UK - starting 1st July 2018

Survival from colorectal cancer (CRC) is strongly related to stage at diagnosis. There is overwhelming evidence that national screening programmes reduce incidence and mortality. Stratified screening could potentially provide a way of improving the efficiency of screening by targeting limited resources to those at highest risk. We have previously published a systematic review of risk prediction models for CRC and externally validated those including phenotypic variables in UK Biobank.

To assess the potential impact of introducing risk stratification using phenotypic or genomic information into the current English bowel screening programme.

The research includes three Work Packages (WP): WP1- An update of our previous systematic review to identify risk models which include genomic information to predict the future incidence of colorectal cancer; WP2- External validation of the risk models identified in WP1 in the UK Biobank cohort; and WP3- Impact and cost-effectiveness analysis to model the potential for population health and impact on the health service if risk stratification using the best performing phenotypic or genomic risk model was introduced into the English bowel screening programme.

Expected outcomes
This work will inform decisions around future stratification of CRC screening programmes using both phenotypic and/or genomic information.