HEDS is part of the School of Health and Related Research (ScHARR) at the University of Sheffield. We undertake research, teaching, training and consultancy on all aspects of health related decision science, with a particular emphasis on health economics, HTA and evidence synthesis.

Wednesday, 18 October 2017

Travel Brocher

Image of Hermance in the Canton of Geneva, Switzerland
Hermance in the Canton of Geneva, Switzerland
Every year the Brocher Foundation, based at Hermance in the Canton of Geneva, Switzerland, funds and hosts residential expert symposia and workshops in its picturesque chateau on the shores of Lake Geneva (see photo).

Next month Dr Andrew Booth from HEDS will be joining international colleagues from the core GRADE-CERQual Working Group, together with representatives from Universities and HTA agencies across the globe, for a three day methods workshop. The workshop is designed to take the GRADE-CERQual system for grading recommendations from qualitative syntheses to its next level of development and offers an opportunity to celebrate the impending appearance of a seven part series on GRADE-CERQual in Implementation Science.  

Tuesday, 17 October 2017

CLAHRC newsletter

From 2008 to 2013 the NIHR funded nine Collaborations for Leadership in Applied Health Research and Care (CLAHRCs) in England.  The CLAHRCs were created to help ensure research evidence was used to improve health services.

The CLAHRC for Yorkshire and Humber region has seveal work themes including Health Economics and Outcome Measurement (HEOM), which is led by Tracey Young.  The HEOM Theme’s third newsletter is now available here.

Monday, 16 October 2017

September’s CEAs.....

Our quick search for CEA’s published in September uncovered 40 articles.   In the right-hand column of this blog is a CEA Archive, which includes our CEA search results by month.  Below are those in our areas of interest.
  • Gray E, Donten A, Karssemeijer N, van Gils C, Evans DG, Astley S, et al. Evaluation of a Stratified National Breast Screening Program in the United Kingdom: An Early Model-Based Cost-Effectiveness Analysis. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2017;20(8):1100-9.
  • Jendle J, Smith-Palmer J, Delbaere A, de Portu S, Papo N, Valentine W, et al. Cost-Effectiveness Analysis of Sensor-Augmented Insulin Pump Therapy with Automated Insulin Suspension Versus Standard Insulin Pump Therapy in Patients with Type 1 Diabetes in Sweden. Diabetes therapy : research, treatment and education of diabetes and related disorders. 2017.
  • Jowett S, Barton P, Roalfe A, Fletcher K, Hobbs FDR, McManus RJ, et al. Cost-effectiveness analysis of use of a polypill versus usual care or best practice for primary prevention in people at high risk of cardiovascular disease. PloS one. 2017;12(9):e0182625.
  • Pearson-Stuttard J, Hooton W, Critchley J, Capewell S, Collins M, Mason H, et al. Cost-effectiveness analysis of eliminating industrial and all trans fats in England and Wales: modelling study. Journal of public health (Oxford, England). 2017;39(3):574-82.

Friday, 13 October 2017

HEDS Discussion Papers available on Open Access database

HEDS produces its own series of discussion papers which started way back in 2001 with a paper by Professor John Brazier, who is now the Dean of ScHARR. The complete series of 137 papers can now be accessed on our own institutional White Rose open access repository. The collection can be viewed and downloaded by going to here

Image of the front cover of the first HEDS Discussion Paper
The first HEDS Discussion Paper 

The series is intended to promote discussion papers in progress. The Views expressed are those of the authors, and therefore should not be quoted without their permission. However, comments are welcome and we ask that they be sent direct to the corresponding author.

Wednesday, 11 October 2017

HEDS international visit to Centre for Infectious Disease Epidemiology and Research

Image of Dr Bell Gorrod with Dr Michael Schomaker, and Professor Mary-Ann Davies
Dr Bell Gorrod with Dr Michael Schomaker,
and Professor Mary-Ann Davies
Dr Helen Bell Gorrod recently visited the Centre for Infectious Disease Epidemiology and Research (CIDER) at the University of Cape Town (UCT). Helen successfully obtained funding for the visit from the Worldwide University Network (WUN) Research Mobility Programme (RMP). 

During the month long visit, Helen worked on a collaborative research project with Dr Michael Schomaker, Professor Mary-Ann Davies and others at UCT. 

The project aimed to assess the impact of delays in viral load testing and treatment switching from first-line to second-line ART treatment regime for HIV patients on hospitalisation and mortality outcomes using causal inference statistical methods. 

Tuesday, 10 October 2017

HEDS in the media - July to September 2017

A lot of the research that ScHARR and HEDS conducts gains media and online attention. As with the last few quarterly periods we have taken a quick look at some the attention using Altmetrics to see what has been said about our work and how far and wide it has reached on social media channels.

HEDS work is regularly mentioned across the media, blogs, social media as well as getting cited in policy documents and Wikipedia entries. On the blog we often take a regular look as to the latest coverage our research receives using Altmetric data that scrapes the web for mentions of our work using DOIs and other unique identifiers. Since the end of June our work and collaborations have received an awful lot of attention. In total we received 3824 total mentions, of which 3,494 were Tweets, whilst we were featured or had our work linked to 101 news articles, 53 blogs and 105 Facebook Shares. HEDS work was also cited 36 times in policy documents (including translated and other versions) and appeared as six Wikipedia citations.

Image of data showing Tweets per country
Tweets by country

Work by Professor Allan Brennan and Colin Angus on impact of local alcohol licensing policies was cited in a The Conversation article and subsequent Yahoo News! story on binge drinkers back in August. Previous alcohol research by Brennan and Angus was also cited in a number of stories in the U.S. starting from Bloomberg and re-run in True Viral News, Arkansas Online, The Journal Gazette, The Keene Sentinel, The Bakersfield Californian and The Salt Lake Tribune. Our work was cited in news across 101 stories, in 69 unique outlets in 13 countries.

Image of graph showing news coverage per country
News coverage by country
Looking at the policy documents, Professor Ben Van Hout’s work before he joined ScHARR is featured in a couple of publications. A paper published back in 1994 for Health Economics is cited in a NICE CDF Rapid Reconsideration on Cetuximab for the treatment of metastatic and/or recurrent squamous cell carcinoma of the head and neck (review of TA172)
Work involving Dr Andrew Booth from a paper published in PLoS Medicine is also cited in the NICE Clinical Guideline; Faltering Growth - recognition and management.

Monday, 9 October 2017

Latest Publications from HEDS in September

Our regular monthly trawl for new publications from HEDS in collaboration with colleagues in ScHARR and further afield never fails to discover fresh research. Many of these are currently in press and you can find much of our work in its open access form via our institutional repository. Tuck in here. 

Image of Journal of Health Economics cover
© Elsevier                              
Brazier J, Rowen DL, Karimi M, Peasgood T, Tsuchiya A, Ratcliffe J. Experience-based utility and own health state valuation for a health state classification system: why do it and how to do it. European Journal of Health Economics

Chambers D, Preston L, Topakas A, de Saille S, Salway S, Booth A, Dawson J, Wilsdon J. Review of diversity and inclusion literature and an evaluation of methodologies and  metrics relating to health research. Available at: https://wellcome.ac.uk/sites/default/files/review-of-diversity-and-inclusion-literature.pdf

Poku EN, Aber A, Phillips P, Essat M, Woods H, Palfreyman S, Kaltenthaler E, Jones G, Michaels J. Systematic review assessing the measurement properties of patient-reported outcomes for venous leg ulcers. British Journal of Surgery

Image of Journal of Epidemiology and Community Health Journal
© BMJ Journals
Sadler S, Tosh J, Pennington R, Rawdin A, Squires H, Romero C, Fischer A, Chilcott J. A cost-effectiveness analysis of condom distribution programmes for the prevention of sexually transmitted infections in England. Journal of Epidemiology and Community Health (2017) 71:897–904. doi:10.1136/jech-2017-209020

Chambers D, Preston L, Salway S, De Saille S, Topakas A, Booth A, Dawson J, Wilsdon JR. The Diversity Dividend: does a more diverse and inclusive research community produce better biomedical and health research? Sheffield: TUOS/Wellcome Trust (2017). Available at: https://wellcome.ac.uk/sites/default/files/the-diversity-dividend-briefing.pdf

Dixon S. Determining the relative cost effectiveness of the fluocinolone acetonide intravitreal implant. Current Medical Research and Opinion (2017) 33:1–2. doi:10.1080/03007995.2017.1366624

Image of PharmacoEconomics Journal
© Adis
Brazier JE, Muston D, Konwea H, Power GS, Barzey V, Lloyd A, Sowade O, Vitti B, Gerlinger C, Roberts. Evaluating the Relationship Between Visual Acuity and Utilities in Patients With Diabetic Macular Edema Enrolled in Intravitreal Aflibercept Studies. Investigative Ophthalmology & Visual Science (2017) 58:4818–4825. doi:10.1167/iovs.17-21945

Bermejo I, Stevenson M, Cooper K, Harnan S, Hamilton J, Clowes M, Carroll C, Harrison T, Saha S. Mepolizumab for Treating Severe Eosinophilic Asthma: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. Pharmacoeconomics (2017) doi:10.1007/s40273-017-0571-8

Bermejo I, Tappenden P, Youn J-H. Response to “Comment on ‘Replicating Health Economic Models: Firm Foundations or a House of Cards?’”. Pharmacoeconomics (2017) doi:10.1007/s40273-017-0574-5

Friday, 6 October 2017

Two Health Economics and Decision Modelling training posts in HEDS

We are currently looking for two Grade 6 Research Assistants.  The posts involve part time working and part time study on the HEDM MSc.  The posts are ideal for researchers with limited experience, or wishing to convert their stats/maths skills into decision modelling and related topics.

If you want to know more, look here.  The closing date is the 8th October.

Thursday, 5 October 2017

NICE budget impact test cleared by High Court

The test, which was introduced this year, states that “if the budget impact exceeds £20million, in any of the first 3 years, NHS England may engage in commercial discussions with the company. These discussions are designed to mitigate the impact that funding the technology would have on the rest of the NHS.”

The ABPI took a legal challenge to the High Court and lost.  NHS England were like a dog with two tails, saying:
“In this ruling the High Court has rejected ABPI’s flawed legal manoeuvres which the judge said would ‘produce an absurd result’. Rather than attempting to further frustrate NICE and the NHS’ work to ensure patients and taxpayers get maximum value out of the £15 billion being spent on drugs, it now makes sense to work together towards that shared goal.”

NHS England chooses which medicine should not be prescribed in primary care

Well, sort of.  It has opened a consultation on “Items which should not be routinely prescribed in primary care: A Consultation on guidance for CCGs”.  It closes on 21st Oct 2017.

Further details can be found here.