HEDS is part of the School of Health and Related Research (ScHARR) at the University of Sheffield. We undertake research, teaching, training and consultancy on all aspects of health related decision science, with a particular emphasis on health economics, HTA and evidence synthesis.

Friday, 16 June 2017

Adaption of HEDS osteoporosis model to use as a case-study

A new project that adapts Sarah Davis' osteoporosis model is being led by Professor Bruce Guthrie at The University of Dundee with the economic component being led by Professor Katherine Payne at The University Manchester. Davis is also included as a co investigator on the project.

Image of bones
CC BY 2.O Ozzy Delaney http://bit.ly/2r9Z3I0

The osteoporosis model was developed by Davis to inform the NICE Multiple Technology Appraisal of Bisphosphonates (https://www.nice.org.uk/guidance/indevelopment/gid-tag462). The adaptation is being carried out by a team of health economists at the University of Manchester, as part of a NIHR funded research project. This is to improve the evidence generated from risk prediction and economic models to better inform decision-making for selecting medicines in people with multimorbidity. This will involve developing new risk prediction tools which account for the competing risks of cardiovascular events, fractures and mortality in patients with multimorbidity. The research project will also examine the impact of incorporating into the cost-effectiveness analysis, a direct utility burden associated with taking a long-term medication which may outweigh the relatively small benefit of preventative medicines.