Children are particularly vulnerable to tuberculosis (TB), with high risks of disease following infection, however diagnosis is difficult and many cases may not receive appropriate care. Even with diagnosis, child-friendly regimens to treat the disease are lacking.
Pete Dodd (HEDS), together with James Seddon at Imperial College, will be beginning a short project for TB Alliance using modelling approaches to estimate the burden of childhood TB from data on adult TB prevalence together with assumptions about how this relates to exposure and progression to disease in children. This will complement estimates based on notifications, and feed into TB Alliance's market sizing work on paediatric TB regimens.
Photo credit: NIAID via Flickr Creative Commons